ea0029p1059 | Male Reproduction | ICEECE2012
Salvolini E.
, Buldreghini E.
, Lucarini G.
, Vignini A.
, Di Primio R.
, Balercia G.
It has been previously shown that human spermatozoa produce nitric oxide (NO), a short-lived free radical synthesised by three isoforms of NO synthase (NOS): endothelial (eNOS), neuronal (nNOS), and inducible (iNOS), which are responsible for the conversion of L-arginine to L-citrulline and NO. Spermatozoa of fertile men express both eNOS and nNOS. The specific roles of NOS isoforms in gametes are not well understood, even if iNOS seems to ...